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This experimental study was planned to detect the changes of fibrinolytic system in the obstetric and gynecological patients. In this strdy, ENZO-DIFFUSION, fibrin plate Test was used to examine the 3 components of fibrimolytic system; available plasmin (fibrinolytic potential), active plasmin (fibrinolysin) and total plasminogen (profibrinolysin). The results were as follows; 1) In normal pregnancy, profibrinolysin was markedly increased in alte pregnancy, and then gradually decreased in labor and after delivery. fibrinolysin was not detected and fibrinolytkc potential was normal in level in late pregnancy and labor and after delivery. 2) In pre-eclampsia and eclampsia; Fibrinolytic potential was normal in level and fibrinolysin was not detected in late pregnancy, in labor and after delivery. But profibrinolysin was less than that of normal pregnancy. 3) In patient with postpartum hemorrhage, profibrinolysin was markedly reduced in level compared to normal postpartum woman. But fibrinolytic potential was normal in level and fibrinolysin was not detected. 4) In two patients with dysfunctional uterine bleeding, although fibrinolytic potentkal was normal in level, profibrinogen was markedly decreased in % activtty and in one of these, fibrinolysin was detected. 5) In a patient given radical hysterectomy for carcinoma of cervix, profibrinolysin was reduced and fibrinolysin was detected on the lst postoperative day. 6) In a patient with hyaline degeneration and suppuration of myoma uteri and panperitonitis profibrinolysin could not be detected pre-and postoperatively, and also, fibrinolytic potential was absent.
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